Huge Breakthrough on TB Vaccine: A groundbreaking approach to tuberculosis (TB) vaccination is set to improve safety and effectiveness. Scientists have engineered self-destructing bacteria that trigger an immune response and then eliminate themselves, reducing risks while enhancing protection.
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TB is a highly contagious disease that primarily affects the lungs. It spreads through the air and remains a leading cause of death worldwide. The current BCG vaccine, developed over a century ago, provides limited protection against adult TB infections. While effective in preventing severe TB in children, its impact on pulmonary TB in adults is inconsistent.
To address this challenge, researchers have modified the bacteria used in TB vaccines. These bacteria now contain built-in “kill switches” that activate after they have stimulated the immune system. Once their job is done, the bacteria self-destruct, preventing any lingering risks in the body. This innovation ensures a stronger immune response while maintaining high safety standards.
Studies on previous TB vaccine improvements showed that higher doses administered through specific methods provided better protection. However, concerns about bacterial persistence in the body remained. The self-destructing mechanism solves this issue by allowing the vaccine to work effectively and then disappear.
This Huge Breakthrough on TB Vaccine could completely change the global TB prevention efforts. By improving the safety and efficiency of vaccines, millions of lives could be saved. Researchers continue the testing and refining of this technology. Self-destructing bacteria could become a key tool in eradicating one of the deadliest infectious diseases in history.
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